Aptamarker™ Platform

DECIPHER BIOLOGY THROUGH THE LENS OF PROTEIN STRUCTURES

A New NGS-Based Tool for Proteomic Discovery

Traditional proteomics tools miss the complexity of in vivo protein structures and modifications (PTMs), leaving critical biomarkers undetected. Aptamarker™ unlocks a deeper layer of biological insight — without needing new equipment.

Aptamarker 100 samples analysis results
Aptamarker™ Kits
Heatmap showing Aptamarker frequencies and correlations
Aptamarker™ Correlation Heatmap - Frequency Analysis and Pattern Recognition

What is Aptamarker™?

Aptamarker™ is an NGS-based proteomics platform that uses a 268-million probe library to detect differences in protein structure and modification — including post-translational changes.

Which bioanalytical challenges does it address?

• Identify proteoforms relevant to diseases by detecting protein structures and post-translational modifications (PTMs) - Multiple epitopes per proteins and macromolecules
• Structural-level protein characterization - Probing the higher order "macroscales" in biological networks
• Analyze and compare samples from any species

What Workflow and Outputs ?

1. Apply kit with 268 million probes to your sample
2. Simple competition assay using FRELEX resin - 90-minute prep, no capital equipment required
3. NGS-based quantification - Combine easily with transcriptomics
4. Bioinformatics output (CSV file of Aptamarker™ frequencies and Aptamarker™ Volcano Plot)

Volcano plot showing differential protein expression analysis
Aptamarker™ Volcano Plot - Differential Protein Expression Analysis

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