DECIPHER BIOLOGY THROUGH THE LENS OF PROTEIN STRUCTURES
A New NGS-Based Tool for Proteomic Discovery
Traditional proteomics tools miss the complexity of in vivo protein structures and modifications (PTMs), leaving critical biomarkers undetected. Aptamarker™ unlocks a deeper layer of biological insight — without needing new equipment.
What is Aptamarker™?
Aptamarker™ is an NGS-based proteomics platform that uses a 268-million probe library to detect differences in protein structure and modification — including post-translational changes.
Which bioanalytical challenges does it address?
• Identify proteoforms relevant to diseases by detecting protein structures and post-translational modifications (PTMs) - Multiple epitopes per proteins and macromolecules
• Structural-level protein characterization - Probing the higher order "macroscales" in biological networks
• Analyze and compare samples from any species
What Workflow and Outputs ?
1. Apply kit with 268 million probes to your sample
2. Simple competition assay using FRELEX resin - 90-minute prep, no capital equipment required
3. NGS-based quantification - Combine easily with transcriptomics
4. Bioinformatics output (CSV file of Aptamarker™ frequencies and Aptamarker™ Volcano Plot)